Continuous subcutaneous insulin infusion versus multiple dose insulin

Suboptimal glycemic control in individuals with diabetes leads to chronic complications and increases mortality. Therefore, efficient glucose control is essential for the prevention of life threatening complications of the disease. The increasing need of aggressive diabetes treatment has led to the improvement of insulin therapy and its implementation techniques. CSII and MDI regimens are the two main intensified insulin regimens. The development of CSII by insulin pumps and shortacting insulin analogues are innovations designed to improve glycaemic control and quality of life (QOL), while limiting adverse effects, such as hypoglycaemia. They represent important advances in the treatment of diabetes.